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Dados do Trabalho
Dermatofibrosarcoma: report of a case with complete response to Imatinib and conservative surgery during the Covid-19 pandemic
Apresentação do caso
In the present study, a case of dermatofibrosarcoma protuberans with local recurrence after surgical
treatment will be reported, subsequently treated with Imatinib and a new surgical approach, with no new
recurrences so far.
Around 85 to 90% of DFSP cases are low-grade tumors, while the fibrosarcomatous variant (DFSP-FS) is associated
with medium and high-grade neoplasms. DFSP affects more young adults, in their 30s [1, 4, 13-15], however, it can
be present in all ages. It has a high potential for locoregional dissemination and recurrence, directly related to
The effectiveness of Imatinib is noted in a deep, infiltrative and relapsed DFSP, in which upfront
surgery would cause significant functional and cosmetic damage. Imatinib allowed an important clinical
improvement for the patient, with tumor reduction in the initial weeks of treatment.
Dermatofibrosarcoma. Imatinib Mesylate. Complementary Therapies
RAFAEL MARTINS STEFFEN, ARTHUR FERNANDES PACHECO, GABRIELA CAMILO TEIXEIRA, BRUNA ALEJANDRA ORELLANA SANTOS, MARINA QUAGLIO OINEGUE FULFARO, KETLEEN KOGA, AMANDA FONSECA NUNES FERREIRA, JAMES COTAET JUNIOR, DEBORAH KRUTMAN ZVEIBIL, RAFAEL RICARDO DA SILVA MIRANDA ZAPATA